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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

2010年英文新年祝福邮件
adj. 荒谬的,可笑的

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

The China-US relationship is crucial not just to the two countries themselves, but also to regional and global peace, security, and stability. Hence we must work together to continuously take it forward.
在这个力求避免任何歧视的态度的年代,年轻一代开始不满邦德的大男子主义态度和不健康的生活方式,因此赫洛维兹引入了一系列会指出邦德错误的新人物。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
From the themed collection: 北京人均GDP突破2万美元
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

“I thought teaching wasn’t a proper career option. My teacher said I’d need to have a high boredom threshold if I wanted to become a teacher,” he recalls.

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 为房产 老人陷入亲情危机
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

A best film nomination looks certain. Darkest Hour's Gary Oldman is the favorite for best actor, but if anyone can beat him it's probably Chalamet.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Richard Waters
销售与市场类
例如,美国和亚洲向投资者推介产品的方式存在明显区别。在亚洲,很大比例的基金(一些人估计为90%)是以佣金为基础。这对ETF不利,因为它们在股票交易所公开交易,在结构上不便向可能推荐它们的银行、券商或理财顾问支付佣金,这与该地区的共同基金行业不同。
Cristiano Ronaldo, the superstar footballer who earned 61 million pound last year, usurped long-term leader Floyd Mayweather Jnr into first place. The retired boxer, who fought just once in the last 12 months, earned pound 30 million.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

London Business School (LBS) performed strongly across all five rankings. All of its programmes are in the European top 10, including its full-time MBAs, ranked second, and its joint EMBA programme (taught with Columbia Business School in the US) and customised executive education courses, both in fourth place.
答:和青木桑一起处理分镜真的是一件很快乐的事呢。有一种“队伍里会有青木桑是毫无疑问的吧“这样的感觉。有了他,相信动画的表现就不会有问题了呢。
有些热门剧已经走得太远,应该降降温了,却仍在大张旗鼓,比如《唐顿庄园》(Downton Abbey)、《丑闻》(Scandal)和《复仇》(Revenge)。ABC频道的新剧《逍遥法外》(How to Get Away With Murder)是一部有趣的替代品,它是一部耸人听闻的夜间肥皂剧,讲述不法辩护律师的故事,简直可以称为“法律与无序”。
他补充说道:“我很兴奋能有机会重返中国,并享受这个国家的文化以及把NBA现场比赛的激动直接带给中国球迷。”

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

Chinese billionaire Wang Jianlin, whose company owns AMC Theaters climbed into the top 20.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
From the themed collection: 定制家具行业新标准已实施
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

特斯拉的积压订单达到2.26亿美元。到2014年之前,特斯拉的生产速度大约为每周1000台,也就是说这些订单需要30周才能消化完。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Xi Jinping and other leadershave made it clear that China is willing to accept a slower growth pace if thiswill allow for a more sustainable, consumer-driven expansion of its economy.Some prognosticators are quick to conclude that China’s economy will soonsignificantly slow down, especially because China’s economy has sputteredfollowing prior instances when the nation’s leaders have effected suchfundamental economic reforms (such as in 1978 and 1993).
《三生三世十里桃花》

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

Other high points for the school include being first for alumni international mobility, second for international experience and third for job placement.
像很多童星一样,玛蒂也显得很早熟。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

今年1月份CPI同比上涨1.8%,去年12月同比上涨为1.6%。不过该指数仍落后于北京方面“3%左右”的目标。
热门的新兴市场基准债券和股票的价格已经下降,同时根据代表全球大型金融公司的组织——国际金融研究所(Institute for International Finance)的数据,来自海外投资者的净流入已经从2014年的2850亿美元降至今年的660亿美元。

Graphical abstract: Diagnostic technologies for COVID-19: a review
From the themed collection: 13城试点租赁住房 保障承租人权利
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

日本三巨头:在本田的美国化管理团队将新品投放市场之前,该公司还会原地踏步,尤其是它的讴歌NSX超跑,这款车型已经在各大车展上亮相好几年了,但至今仍未上市。本田CEO卡洛斯o高森一边督促高管团队努力实现他的“三年计划”目标,一边培养继承人。《汽车新闻》报道称,丰田公司在携新产品搬离南加州工厂之前,正处于“马力全开”的状态。
6.当我看球赛时,禁止从电视前面经过,你最好是从地板上爬过去以免影响我看球。
Brands with the most incentive to coast in 2015:Jeep, which must be exhausted after lifting sales an astonishing 44% on the back of the new Cherokee, and Subaru, now the 10th most popular brand in America after improving its sales by 21% in its usual fashion: quietly.
May the glow of New Year candle fill your heart with peace and pleasure and make your New Year bright.Have a love filled New Year!愿新年的烛光带给你祥和与喜悦,祝你新年充满爱。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Yes, it is that obvious when you're interviewing elsewhere and go MIA, with or without a flimsy excuse. Schedule phone interviews for personal hours, like a lunch break, and take vacation or PTO days for lengthy in-person interviews. "That way, you're not feeling pressured during the interview to get back to work – which can affect how you handle the interview – and you're not stealing time from your employers," Kay says。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

The Fate of the Furious was the top-grossing foreign film, ranking second on the list.
Only asset management firms saw profits rise, up 16.7 per cent year-on-year to Rmb3.7bn.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Detroit Three: The other two Michigan-based manufacturers still face bumps. General Motors copes with continued fallout from its ignition switch recall while Ford fights through the most aggressive launch period in the company’s history.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

n. 争斗,战斗

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

The survey by the Public Religion Research Institute in partnership with the Religion News Service found political and religious disagreement on what is behind severe weather, which this year has included extreme heat and drought.
But what about the tens of thousands of Irish fans? They're out of control.
Given that every single Wall Street economist had called for higher rates at the start of this year and 67 of 67 economists surveyed by Bloomberg concurred, the rate-sensitive utilities industry would have been the last sector a rational person would want to overweight. Bets on the financial sector were slow to pay off while wagers on “cheap” energy stocks demolished portfolio performance in the third and fourth quarters, just as they had elevated it during the first and second.
全球最佳大学排行榜是根据科睿唯安公司提供的数据和标准得出的。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

And while many Bond girls fade into acting obscurity or fall into second-class flicks after making a 007 splash, Marlohe and her agents at ICM Partners are making sure the actress surrounds herself with top-flight talent as she uses the Bond movie as a launching pad for an international career.
凯瑟琳·毕格罗和编剧马克.波尔已经为了这部电影筹备了一段时间,影片讲述的是1967年发生在底特律的警方突袭行动,这次行动引发了美国历史上规模最大的一场民众暴动。出演该片的有凯特林.德弗、约翰.卡拉辛斯基、威尔.保尔特、约翰.波耶加以及杰克.莱诺。
Did you have to worry about these little things when you were my age? 在您那个年代,您曾经担心过我们现在担心的事吗?
像中国人口这么多的国家,关于寂寞的病毒式模仿会这么流行实在是件很讽刺的事情。这句看上去很无厘头的话被用在了所有可能搭配的排列中,用在了所有场合,比如,“哥看的不是书,是寂寞。”
Russian President Vladimir Putin took a 10% pay cut last year, as his country sank into a deep recession. But that was after his salary more than doubled in April 2014, to roughly 9.7 million rubles.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

单词eccentric 联想记忆:
他说:“黄金披萨奢华至极。如果你想享受一顿奢侈大餐,那么这份披萨就是为你准备的。”

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

世界杯锦标赛即将到来。 我想告诉你永葆美丽的一些要诀。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

鹈鹕一直在费力的吸引并留下自由球员,他们必须在这个夏天留下朱-霍勒迪,考辛斯的家乡在附近的阿拉巴马,而且他和安东尼-戴维斯是密友,同时,多个令人沮丧和伤病困扰的赛季让鹈鹕一直在失败的循环中摇摆。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

“这是真的“我必须去做这件事”的时刻了,”他说。
contain
德里克·罗斯
“而在市场上前所未有的是确实有客户在寻找这样的投资。”

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

报告结果基于今年8月、9月针对全国15870位民众开展的调查。
根据QS的这一排名,使得中国成为入选全球400强学校第二多的国家,仅次于有164所大学的学科入选全球400强的美国。英国排名第3,有78所大学进入榜单。
据另一家市场研究公司Counterpoint的统计数据显示,中国去年智能手机总出货量达到了4.65亿台,占据全球总量的近三分之一。
最近的例子也比比皆是,从乌戈.查韦斯(Hugo Chávez)到欧尔班.维克托(Viktor Orban)和弗拉基米尔.普京(Vladimir Putin)。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

公司:建筑公司Project Frog
9.亲爱的贵客们,我们希望英国能为你们贡献一个美好的夏天,这个夏天包括了顶尖的国际赛事、先进的设施、有趣的娱乐、以及汇集了几个世纪的艺术建筑精华的文化遗产。如果你最终只收获了四张卓著国际中心的摔跤比赛门票,好吧,祝你下次好运。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Jackdaw Research的简?道森(Jan Dawson)表示,最近几个月“他表现得更加意气风发和充满自信”。
现在基本上只能依靠其他制度(尤其是国会、法庭和媒体)以及公民。
2. Audiologist
俄罗斯把自己看作超级大国 -- 这在国内是毋庸置疑的。
“Insead enormously boosted our intercultural experience,” said one alumni survey respondent from Switzerland. “It is a place to learn global culture better than anywhere else.”

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

首次发现直接由禽类传染人类的流感病毒,此病毒的传染与接触家禽市场有关。香港有六人死亡。这种病毒之所以不同,是因为它并没有通过传染猪,使猪成为中间宿主,而是直接由鸡传染给人类。另外,年轻人中感染最严重的病症有些与1918年“西班牙流感”病毒相似。
The ministry said that it had no tolerance for cheating and had asked public security departments to conduct an investigation.
"Another interesting aspect of this year's list is that more short numerical passwords showed up even though websites are starting to enforce stronger password policies."

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

但我预计其他银行将效仿此举。在不涨薪的前提下,任何让优秀员工保持活力和积极性的办法都值得考虑。
2011年在达洛伊西奥15岁时,他就曾获得来自李嘉诚的种子投资。一年之后Summy发布,并在短短一个月内吸引了500,000名用户,在28个国家登上了新款应用软件热度榜的首位。对于一个连高中都还没毕业的人来说,雅虎的收购可谓意义深远。不过,达洛伊西奥的过人之处可不只是技术知识丰富这一点。在他连胡子都不用刮的时候,他就强烈向往、渴望著有朝一日能在科技领域做出一番大的成就。不仅要创新,还要有所成就,当然,还要大把赚钱。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

Apple Inc. CEO Steve Jobs introduces the iPad 2 on stage during an Apple event in San Francisco, California in this March 2, 2011,
平均工作经验:12个月
adj. 无限的,无穷的

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

12) I often find myself worrying about something 0 1 2 3 4
n. [计]定序;排序;订购 v. 命令;指挥;订购(o
The third gunman, Amedy Coulibaly, who stormed a kosher supermarket on Friday,never left for such training, said Valls.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
From the themed collection: 橱柜衣柜市场未来10年风口已现
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

The 22-year-old Lawrence is the face of "The Hunger Games" franchise, and she may earn an Oscar nomination for her performance in "Silver Linings Playbook."

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

美国全国地产经纪商协会(National Association of Realtors)的数据显示,自去年7月份以来美国成屋销量每月都在下滑。这和美国借贷成本上升是同步的。由于美联储暗示将缩减购债计划的规模,整个经济的借贷成本不断上升。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

Song “The Spring Blossom” (Na Ying)
n. 薄片,切片

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
From the themed collection: 楼市将进入长效机制构建轨道
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

其他国家的监管机构将以日本模式的成功或失败为借鉴。
6. Smart refrigerator
One of the country's largest clinics, JK Plastic Surgery Center founded by Joo Kwon, recently opened a hotel to better serve customers, who spend an average of $17,675 during a single visit.
如果此时打断老师讲课不太合适,你可以快速记下自己的问题,以免忘记,之后再问老师。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

"He was not on the intelligence services' radar," added the prime minister.
如果时间允许的话,Fossil建议逐步完善你在领英上面的简介(这样可以不会太明显)或者最好的是你还没找工作的时候就完善它。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

大宗农产品投机交易一直是今年市场波动的一个特点,荷兰合作银行预测,这种趋势将继续。
[tr?ns'p?:t]

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

中俄双方经贸合作的潜力很大,互补性很强,双方所达成的经贸关系目标是可以实现的。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

n. 锦标赛,冠军,拥护
China has ample foreign exchange reserves to satisfy the demands of imports and short-term debt repayments.
At the same time, Apple is bringing in costly new components. These include an OLED display that makes the front of the phone into one continuous screen. Depth-sensing cameras will offer new “augmented reality” features and allow the device to be unlocked by face recognition, instead of fingerprint.
Epic Games在网站Kotaku上发表的一份声明中则指出,提起法律诉讼的原因是罗杰斯在一个YouTube视频的可移除标签上写下了涉及DMCA的反诉内容,这段视频展示并推广了《堡垒之夜》外挂软件。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
From the themed collection: 27日港股内房板块再度大涨
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

单词slouch 联想记忆:
Promote all-round economic, political, cultural, social, and ecological progress

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

根据官方数据显示,今年前10个月中国对外非金融类投资同比下降40.9%,这反映出中国政府严格的资本管控带来持续影响。
3. Economy is already crashing, GDP will get even worse in 2014-2016
今年,标普500指数的总回报率为14%,比该指数25年期平均年化收益率高出40%。过去12个月,华尔街的首席战略师们一直在上调其目标值。标普500指数出现了50多次创纪录的收盘,几乎所有专业投资管理人士都卯足了劲,至少要跑平该指数。但有些因素让美股投资者要获得高于基准股指的收益,在今年尤为困难。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

“Even though I’m an engineer and an analytical person at heart, the most important decisions I’ve ever made had nothing to do with any of that,” he told an interviewer at Duke University, where he studied for an MBA, last year. “They were always based on intuition.”
It Pays to Get Along
Meanwhile, villages within the city's boundaries will be overhauled and low-end manufacturers and logistics companies removed.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

I'm pleased to see manufacturing jobs returning to the U.S., but I don't expect the manufacturing industry to have the galvanic effect on the economy that many hope for. Why? Because automation will sharply erode the number of jobs any factory requires. The disappearance of blue-collar and entry-level jobs is already a problem, and that problem will grow.
7、《海底总动员2》

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
From the themed collection: 地暖致癌 地板是助推者
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

The piece was taken away for laboratory testing, and the Spielman family only received a phone call this month telling them the amulet had been identified.
哈维尔以自己的名字开了一个储蓄账户,并且用这些信息注册了AdWords账户。
对于其他队伍而言,在球场上拥有良好判断力的德国也是一直非常出色的队伍。意大利也是世界杯上无法忽视的队伍,而拥有罗纳尔多的葡萄牙队将会是一直极具危险性的队伍。拥有众多的大将的比利时队也将成为人们口中津津乐道的黑马队伍。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

眼下,合格的供应链经理极度缺乏,在那些分支机构遍布全球的跨国公司中尤其如此。究其原因,不外以下两点。
"Well, I believe I am a feminist because I believe that women deserve the same rights as men in every aspect of our economy and our society, here at home and around the world," Clinton said to applause. "You know, I've devoted a lot of my public life to advocating for women's rights being human rights, and making the case that we have to do everything we can, through laws, regulations, culture, to change the still-existing stereotypes that hold women back."

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

4. Slacking at school
While Kobe's grown into his 6'6'' frame nicely, he was still a pretty decent-sized guy back in high school. Just imagine how hard trying to stop a 17-year-old Kobe Bryant was back in 1996. I'm sure it was nearly impossible.
Wealthy Chinese bought at least seven overseas islands in 2014.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

‘Faultless performance, you are stunning and you could win this competition,’ Amanda said.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
From the themed collection: 全国建材家居巨头长沙论剑
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

5.Paperpot Transplanter
Never accept the job immediately. Say you need to think about it overnight. Once you sign on the dotted line there's no room for negotiation.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
From the themed collection: 荣麟家居启动线上打假
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

约28000枚炸弹和其他弹药在只有俄亥俄大小的南斯拉夫境内爆炸。时任国防部长的威廉·科恩将联军描述为“史上最精确的空中力量运用”。500余名平民在消耗巨量弹药的轰炸中丧生,这一数字出乎意料的低。北约在自己的作战报告中着重强调:所有目标都经过“仔细甄别”,并且“付出了巨大努力以将空袭行动对塞尔维亚平民的影响降到最低”。
去年12月,包括中国商务部、中国央行在内的四个政府部门表示,将收紧对房地产、酒店、影城、娱乐业、体育俱乐部等领域的“非理性”对外投资项目的审查。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

时间:2009-10-22 编辑:vicki
1. Buy expensive tailored clothing that only sort of fits so that most of the time your buttons appear to be just seconds from bursting.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

After working for half a year, the average monthly income for 2014 graduates is RMB3,487, a significant increase from RMB3,250 in 2013 and RMB3,048 in 2012.
loan

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

mask

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
From the themed collection: 迎接2.0时代绿建行业整装待发
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

刘易斯呼吁那些不能再照顾自己宠物的人们要联系家人、邻居或者动物收容所来接手这些动物。
Prices in popular emerging market debt and equity benchmarks have already fallen, while net inflows from overseas investors have dropped from $285bn in 2014 to $66bn this year, according to the Institute for International Finance, a group representing the world’s largest financial companies.
For starters, breaches like that of Bitstamp and the much larger (valued at about $400 million at the time) 2011 hack of the exchange Mt. Gox are often misconstrued as security issues with the currency itself. But they are only signs of flaws in those particular exchanges and not a sign of an issue with the underlying technology. And it is the underlying technology behind bitcoin that most excites. As we wrote in the “Shape the Future” package of our January 2015 issue, most of the vocal enthusiasts so bullish on bitcoin—from big-name entrepreneurs like Marc Andreessen to the developers and miners who spend their days refreshing the bitcoin Reddit page—are more interested in the applications that can be built on bitcoin’s “block chain,” the currency’s foundational backbone, than they are in bitcoin as a monetary system. The block chain allows the secure exchange of any form of value between two entities.
“我们为最佳影片奖颁奖通告期间出现的失误,向《月光男孩》、《爱乐之城》、沃伦?比蒂、费?唐纳薇、以及奥斯卡奖观众表示诚挚地道歉。颁奖嘉宾收到的是错误奖项的信封,这个失误一经发现立刻得到了纠正。”

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

P2P lending has grown quickly in the past two years, with loans outstanding reaching Rmb209bn by the end of June, according to E-Lending House.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

Letizia Battaglia chronicled Palermo’s Mafia wars in the 1970s and ’80s for a local newspaper. Now, her images appear in museums and retrospectives.
好市多首席执行官克雷格杰利内克
Condos and co-ops have been laying down the law, writing warning memos and fining wayward residents. For renters, breaking the rules could jeopardize a lease. Condos are tightening security, asking doormen to scrutinize visitors and requiring residents to sign authorization forms for guests. The practice has also raised insurance concerns.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

The global survey was conducted between 2010 and 2012 and follows the Earth Institute's first rankings released last year. While "the world has become a slightly happier and more generous place over the past five years," economic and political upheavals have resulted in greatly reduced levels of well being for some nations, the report said.
To Rouslan Krechetnikov and Hans Mayer for studying the dynamics of liquid-sloshing, to learn what happens when a person walks while carrying a cup of coffee. I`ll give you a hint: it happens between step 7 and 10.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

世界知识产权组织总干事弗朗西斯·居里表示:“投资创新是提高长期经济增长的关键。在当前的经济形势下,发现新的增长来源并利用全球创新所带来的机会是所有利益相关者的优先事项。”
年龄:33岁

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

Brain death is a bit of an inconvenience if you're a fan of living, and if you're looking to replace yours with a spare, you're out of luck. Sure, maybe we'll one day be able to plant brains into skulls, but the brain's not just another organ. It contains all your thoughts and memories. They can plop a new brain in your head, but you'll still be gone, so the idea of making artificial brains may seem absurd.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

根据这份由互联网薪酬调查及报告提供商中国薪酬网发布的调查显示,清华大学2017届毕业生平均月薪达9065元。
台风哈维
物理学界这一开拓性的发现已经点燃科学研究的星星之火,而他们的这项研究发展为前沿科技,也不过是时间早晚的事罢了,就像100年前我们无法想象今天的激光和电脑芯片那样,美国物理学会候选会长劳拉?H?格林在接受《纽约时报》采访时表示。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

他仅面临这几个障碍:他的手下、国会里的共和党人以及总统行政权的限度。而这几个障碍都非常有分量。他竞选时声称要对中国货物征收45%关税的承诺,已经变成对中国知识产权做法展开调查。
工业生产者出厂价格指数(PPI)通常被认为是中期通胀的代表,该指数仍留在负值区间,但下降速度有所放慢。
Mr. Lyons took a casting of Ms. Swinton’s mouth and designed teeth to fit. Those were clipped on over Ms. Swinton’s real teeth. For Minister Mason, he came up with a quirky look but didn’t quite want it to be comical. He was, however, interested in adding a little bling. “There’s a little bit of gold on the left-hand side,” he said. “We used real gold to make the filling of one tooth. We did it to put more character into the character.”
10.I thought I already sent that email out. I’m sure I did. – Because telling you that it was a low priority and I forgot would probably hurt our relationship。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

乔纳森·格雷泽导演的《皮囊之下》讲述的是一位美丽又可怕的外星人的故事,她本身美丽,恐怖而且是个外星人:这是一部完全与众不同的,残暴的色情电影。乔纳森·格雷泽以前导演的优秀作品仅仅只是为这部电影做的局部模糊的铺垫。他的《性感野兽》(2000)是一部令人视觉上满足的,兴奋的,充满智慧的犯罪惊悚片,它超越了那个年代操着方言的悲剧老头的模式。《重生》(2004)有着库布里克式的精致与阴冷,电影中的一些画面,十分出色;它是一部值得奉为经典的电影,但尚未实现。接着十年过去了,对那些电影事业一直无法实现的人,格雷泽似乎成为他们的设计师。(天知道,这种事情总发生在那些有天赋的人身上)。
新晋的富翁包括第一位以戏剧制作人身份进入榜单的卡梅隆·麦金托什,WeWork的亚当·诺依曼和米格尔·麦凯尔维,以及图片分享网站Pinterest的创始人本·希伯尔曼和埃文·夏普。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: 内蒙古商品房待售面积持续下降
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

不要马上接受工作录用
The “cool” factor isn’t the only issue. Security and privacy, particularly around the management of consumer data, remain a concern as the tech industry seeks to bring more of our body parts online. As The Economist notes, the glamour of developing sensors and algorithms for wearables is distracting everyone from glaring missing elements, “standards, interoperability, integration and data management” and “intellectual-property rights and regulatory compliance” among them. All this in an environment where paranoia remains over the National Security Administration’s activities.
The company is hardly alone in its efforts to woo talent of a different sort. Earlier this year Intel announced a collaboration with the Council of Fashion Designers of America, or CFDA, kicking off a partnership with the high-concept retailer Opening Ceremony to design its smart bracelet. Tory Burch partnered with Fitbit to design pendants and bracelets akin to the Shine Tracker by Misfit Wearables. And Apple AAPL -1.03% has tapped a diverse group of people, including former Burberry chief executive Angela Ahrendts (to lead its retail efforts), former Yves Saint Laurent CEO Paul Deneve, and former Nike NKE -0.71% design director Ben Shaffer.

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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Last year he told an interviewer that 'among others' he would be giving his riches to Choupette.
4.Avoid micromanaging

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